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Check Intently (1)pentobarbital will minimize the level or influence of fentanyl transdermal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely. Coadministration of fentanyl with CYP3A4 inducers may lead to your minimize in fentanyl plasma concentrations, insufficient efficacy or, maybe, improvement of the wi